In collaboration with the Tanzania National Institute for Medical Research (NIMR) and London School of Hygiene and Tropical Medicine (LSHTM)

An international multi-centre, randomised, double-blind, placebo-controlled trial to evaluate the efficacy and safety of 0.5% and 2% PRO 2000/5 gels for prevention of vaginally acquired HIV infection

Principal Investigators: Richard Hayes, Saidi Kapiga

Chief Investigators of the multi-centre trial: Charles Lacey (University of York, UK), Sheena McCormack (MRC Clinical Trials Unit)

Co-Investigators: Caroline Allen (LSHTM), Celia Barberousse (LSHTM), Claire Cook (LSHTM), John Changalucha (NIMR), Sheila Harvey (LSHTM), Shelley Lees (LSHTM), Joseph Masanja (AMREF), Claire Moffat (AMREF/LSHTM), David Ross (LSHTM), Andrew Vallely (AMREF/LSHTM), Deborah Watson-Jones (LSHTM)

Funding: DFID and MRC to the Microbicides Development Programme (MDP), a consortium of UK and African institutions

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A study to determine the feasibility of conducting a microbicide trial of daily vaginal gel and to inform the way adherence should be assessed (Top-Up study)

Principal Investigators: Saidi Kapiga, Richard Hayes

Project Coordinators: Joseph Masanja, Sheila Harvey, Grace Mtolela

Funding: DFID and MRC to the Microbicides Development Programme (MDP), a consortium of UK and African institutions

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Capacity development and strengthening in preparation for HIV vaccine trial in Tanzania and Burkina Faso

Principal Investigator: Saidi Kapiga

Project Coordinators: Harr Freeya Njai, Aika Mongi

Funding: European and Developing Countries Clinical Trials Partnership (EDCTP)

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Intravaginal Practices in Tanzania and Uganda: relationships with vaginal microenvironment, HIV and other STIS (intravaginal practices project)

Principal Investigators: Richard Hayes, Saidi Kapiga

Project Coordinators: Suzanna Francis, Bahati Andrew, Kaballa Maganja

Funding: UK Medical Research Council (MRC); International Partnership of Microbicides (IPM); European and Developing Countries Clinical Trials Partnership (EDCTP)

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Evaluation of the long-term impact of an adolescent sexual health intervention programme (MEMA kwa vijana) in Mwanza, Tanzania: a community randomised controlled trial

Principal Investigators: David Ross, John Changalucha, Richard Hayes, Sheena McCormack, Deborah Watson-Jones

Project Coordinators: Aoife Doyle (LSHTM), Kaballa Maganja (MITU)

Funding: UK Department for International Development (DFID), and Irish Aid, Ireland

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